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The antibody against ESAM was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 30-248 of human ESAM (NP_620411.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ESAM was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 30-248 of human ESAM (NP_620411.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02245A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ESAM |
| Target Synonyms | W117m; ESAM | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, A-549, HepG2, HT-29 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 30-248 of human ESAM (NP_620411.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96AP7 | Immunogen Sequence |
Uniprot Id
Q96AP7
Target Species
Human
Target Name
ESAM
Target Full Name
Endothelial cell-selective adhesion molecule
Target Function
Can mediate aggregation most likely through a homophilic molecular interaction.
Target Subcellular Location
Cell junction, adherens junction. Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Highly expressed in endothelial cells.
Target Research Area
Cell Adhesion
Target Synonyms
2310008D05Rik; Endothelial cell adhesion molecule; Endothelial cell selective adhesion molecule; Endothelial cell-selective adhesion molecule; Esam; ESAM_HUMAN; HUEL (C4orf1) interacting protein ; LP4791 protein ; W117m
Target Background
Enables cell-cell adhesion mediator activity. Involved in several processes, including bicellular tight junction assembly; cell-cell adhesion; and regulation of actin cytoskeleton organization. Located in cell-cell junction and plasma membrane. Part of protein-containing complex.
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