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The antibody against ETFDH was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 318-617 of human ETFDH (NP_004444.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ETFDH was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 318-617 of human ETFDH (NP_004444.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09461A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ETFDH |
| Target Synonyms | MADD; ETFQO; ETFDH | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Rat heart, Mouse liver, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 318-617 of human ETFDH (NP_004444.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q16134 | Immunogen Sequence |
Uniprot Id
Q16134
Target Species
Human
Target Name
ETFDH
Target Full Name
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
Target Function
Accepts electrons from ETF and reduces ubiquinone.
Target Involvement
Glutaric aciduria 2C (GA2C)
Target Subcellular Location
Mitochondrion inner membrane.
Target Protein Families
ETF-QO/FixC family
Target Research Area
Metabolism
Target Synonyms
Electron transfer flavoprotein ubiquinone oxidoreductase; Electron transfer flavoprotein-ubiquinone oxidoreductase; electron transferring flavoprotein dehydrogenase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase; ETF QO; ETF ubiquinone oxidoreductase; ETF-QO; ETF-ubiquinone oxidoreductase; ETFD_HUMAN; Etfdh; MADD; mitochondrial
Target Background
This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain. Mutations in this gene are associated with glutaric acidemia. Alternatively spliced transcript variants that encode distinct isoforms have been observed.
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