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Rabbit anti-Human ETV7 Polyclonal Antibody

The antibody against ETV7 was raised in rabbit using the Fusion protein of Human ETV7 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-30094A

The antibody against ETV7 was raised in rabbit using the Fusion protein of Human ETV7 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-30094A ClonalityPolyclonal
Host SpeciesRabbitTarget NameETV7
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human ETV7Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y603
Background Information
  • Uniprot Id

    Q9Y603

  • Target Species

    Human

  • Target Name

    ETV7

  • Target Full Name

    Transcription factor ETV7

  • Target Function

    Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    ETS family

  • Target Tissue Specificity

    Expressed in hematopoietic tissues.

  • Target Synonyms

    ETS related protein Tel2; Ets transcription factor TEL-2b; Ets transcription factor TEL2; ETS translocation variant 7; ets variant 7; ets variant gene 7 (TEL2 oncogene); ets variant gene 7; ETS-related protein Tel2; ETV7; ETV7_HUMAN; TEL 2; Tel related Ets factor ; Tel-related Ets factor; TEL2 ; TEL2 oncogene; TELB; Transcription factor ETV7; Transcription factor Tel 2; Transcription factor Tel-2; TREF

  • Target Background

    The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).

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