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The antibody against EXOC3 was raised in rabbit using the Recombinant Human Exocyst complex component 3 protein (410-756AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, antigen affinity purified & affinity purified with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against EXOC3 was raised in rabbit using the Recombinant Human Exocyst complex component 3 protein (410-756AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, antigen affinity purified & affinity purified with a purity greater than 95%. This antibody has been validated on ELISA, WB.
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Western Blot | Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, A549 whole cell lysate, HL60 whole cell lysate, PC-3 whole cell lysate, U87 whole cell lysate | All lanes: EXOC3 antibody at 1:2000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 87, 74, 86 kDa | Observed band size: 87 kDa
| Cat.No | ADC-00657A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EXOC3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Antigen Affinity purified & Affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Exocyst complex component 3 protein (410-756AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60645 |
Uniprot Id
O60645
Target Species
Human
Target Name
EXOC3
Target Full Name
Exocyst complex component 3
Target Function
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Target Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Midbody. Golgi apparatus. Cell projection, neuron projection.
Target Protein Families
SEC6 family
Target Tissue Specificity
Expressed in epididymis (at protein level).
Target Synonyms
EXOC 3; Exoc3; EXOC3_HUMAN; Exocyst complex component 3; Exocyst complex component Sec 6; Exocyst complex component Sec6; rSec 6; Sec 6; Sec 6 homolog; Sec 6p; Sec6; SEC6 L1; SEC6 like 1; Sec6 protein; SEC6L1; Sec6p
Target Background
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
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