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Rabbit anti-Human EXOC4 Polyclonal Antibody

The antibody against EXOC4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human EXOC4 (NP_068579.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02336A

The antibody against EXOC4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human EXOC4 (NP_068579.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-02336A ClonalityPolyclonal
Host SpeciesRabbitTarget NameEXOC4
Target SynonymsSEC8; Sec8p; SEC8L1; EXOC4FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesRat brain, A-431, Jurkat, Mouse brain, Mouse liver, Mouse thymusApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human EXOC4 (NP_068579.3).Target SpeciesHuman
Uniprot IDQ96A65Immunogen Sequence
Background Information
  • Uniprot Id

    Q96A65

  • Target Species

    Human

  • Target Name

    EXOC4

  • Target Full Name

    Exocyst complex component 4

  • Target Function

    Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

  • Target Subcellular Location

    Midbody, Midbody ring. Cell projection.

  • Target Protein Families

    SEC8 family

  • Target Synonyms

    dSec8; EXOC 4; Exoc4; EXOC4_HUMAN; Exocyst complex component 4; Exocyst complex component SEC8; KIAA1699; MGC27170; REC 8; REC8; rSec 8; Sec 8; Sec 8p; Sec8; SEC8 like 1; SEC8 protein; Sec8L1; Sec8p

  • Target Background

    The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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