Rabbit anti-Human FABP2 Polyclonal Antibody

Uniprot Id

P12104

Target Species

Human

Target Name

FABP2

Target Full Name

Fatty acid-binding protein, intestinal

Target Function

FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

Target Subcellular Location

Cytoplasm.

Target Protein Families

Calycin superfamily, Fatty-acid binding protein (FABP) family

Target Tissue Specificity

Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.

Target Research Area

Cardiovascular

Target Synonyms

FABP 2; FABP2; FABPI; FABPI_HUMAN; Fatty acid binding protein 2 intestinal; Fatty acid binding protein; Fatty acid binding protein intestinal; Fatty acid-binding protein 2; Fatty acid-binding protein; I FABP; I-FABP; IFABP; intestinal; intestinal FABP; Intestinal fatty acid binding protein 2; Intestinal-type fatty acid-binding protein; MGC133132; OTTHUMP00000163925

Target Background

The protein encoded by this gene is an intracellular fatty acid-binding protein that participates in the uptake, intracellular metabolism, and transport of long-chain fatty acids. The encoded protein is also involved in the modulation of cell growth and proliferation. This protein binds saturated long-chain fatty acids with high affinity, and may act as a lipid sensor to maintain energy homeostasis.