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The antibody against FAM3B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human FAM3B (NP_478066.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IHC-P, IF/ICC, ELISA.
The antibody against FAM3B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human FAM3B (NP_478066.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IHC-P, IF/ICC, ELISA.
Immunohistochemistry analysis of paraffin-embedded human colon using FAM3B antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
| Cat.No | ADA-09123A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FAM3B |
| Target Synonyms | 2-21; ORF9; PANDER; PRED44; C21orf11; C21orf76; FAM3B | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human FAM3B (NP_478066.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P58499 | Immunogen Sequence |
Uniprot Id
P58499
Target Species
Human
Target Name
FAM3B
Target Full Name
Protein FAM3B
Target Function
Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner.
Target Subcellular Location
Secreted. Note=Present in insulin secretory granules and likely cosecreted with insulin. Localized in discrete vesicular and perinuclear structure.
Target Protein Families
FAM3 family
Target Tissue Specificity
Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis.
Target Research Area
Immunology
Target Synonyms
2-21; C21orf11; C21orf76; Cytokine like protein 2 21; Cytokine-like protein 2-21; Fam3b; FAM3B_HUMAN; Family with sequence similarity 3 member B; ORF9; Pancreatic-derived factor; PANDER; PRED44; Protein FAM3B
Target Background
Involved in insulin secretion. Located in extracellular exosome.
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