Rabbit anti-Human FAM62B Polyclonal Antibody

The antibody against FAM62B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 630-760 of human FAM62B (NP_065779.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03270A

Number

Cat.No	ADA-03270A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	FAM62B
Target Synonyms	E-Syt2; FAM62B; CHR2SYT	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney, HT-29, Mouse liver, U-87MG	Application	ELISA, WB

Cat.No

ADA-03270A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

FAM62B

Target Synonyms

E-Syt2; FAM62B; CHR2SYT

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney, HT-29, Mouse liver, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 630-760 of human FAM62B (NP_065779.1).	Target Species	Human
Immunogen Sequence	EKRERPPDHQHSAQVKRPSVSKEGRKTSIKSHMSGSPGPGGSNTAPSTPVIGGSDKPGMEEKAQPPEAGPQGLHDLGRSSSSLLASPGHISVKEPTPSIASDISLPIATQELRQRLRQLENGTTLGQSPLG	Uniprot ID	A0FGR8

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 630-760 of human FAM62B (NP_065779.1).

Target Species

Human

Immunogen Sequence

EKRERPPDHQHSAQVKRPSVSKEGRKTSIKSHMSGSPGPGGSNTAPSTPVIGGSDKPGMEEKAQPPEAGPQGLHDLGRSSSSLLASPGHISVKEPTPSIASDISLPIATQELRQRLRQLENGTTLGQSPLG

Uniprot ID

A0FGR8

Background Information

Uniprot Id

A0FGR8
Target Species

Human
Target Name

ESYT2
Target Full Name

Extended synaptotagmin-2
Target Function

Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS).
Target Subcellular Location

Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families

Extended synaptotagmin family
Target Tissue Specificity

Widely expressed with high level in cerebellum.
Target Research Area

Cell Biology
Target Synonyms

ESYT2; FAM62B; KIAA1228Extended synaptotagmin-2; E-Syt2; Chr2Syt
Target Background

Enables calcium ion binding activity; identical protein binding activity; and phospholipid binding activity. Predicted to be involved in endocytosis; endoplasmic reticulum-plasma membrane tethering; and lipid transport. Located in endoplasmic reticulum-plasma membrane contact site. Is extrinsic component of cytoplasmic side of plasma membrane; integral component of plasma membrane; and intrinsic component of endoplasmic reticulum membrane.

Rabbit anti-Human FAM62B Polyclonal Antibody

Specifications

Immunogen Information

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