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The antibody against FANCE was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human FANCE (NP_068741.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against FANCE was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human FANCE (NP_068741.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01387A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FANCE |
| Target Synonyms | FAE; FACE; FANCE | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse thymus | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human FANCE (NP_068741.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9HB96 | Immunogen Sequence |
Uniprot Id
Q9HB96
Target Species
Human
Target Name
FANCE
Target Full Name
Fanconi anemia group E protein
Target Function
As part of the Fanconi anemia (FA) complex functions in DNA cross-links repair. Required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2.
Target Involvement
Fanconi anemia complementation group E (FANCE)
Target Subcellular Location
Nucleus.
Target Synonyms
2810451D06Rik; AI415634; AW209126; FACE; FAE; FANCE; FANCE_HUMAN; Fanconi anemia complementation group E; Fanconi anemia group E protein; OTTHUMP00000016254; Protein FACE; RGD1561045
Target Background
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E.
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