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The antibody against FARP2 was raised in rabbit using the Synthesized peptide derived from Internal of Human FIR. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against FARP2 was raised in rabbit using the Synthesized peptide derived from Internal of Human FIR. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from HuvEc cells, using FIR antibody.
| Cat.No | ADC-42197A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FARP2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Internal of Human FIR. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O94887 |
Uniprot Id
O94887
Target Species
Human
Target Name
FARP2
Target Full Name
FERM, ARHGEF and pleckstrin domain-containing protein 2
Target Function
Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion.
Target Research Area
Neuroscience
Target Synonyms
FARP2; FARP2_HUMAN; FERM; FERM domain including RhoGEF; FERM; RhoGEF and pleckstrin domain protein 2; FERM; RhoGEF and pleckstrin domain-containing protein 2; FGD1 related Cdc42 GEF; FIR; FRG; KIAA0793; PH domain-containing family C member 3; Pleckstrin homology domain-containing family C member 3; PLEKHC3; RhoGEF and pleckstrin domain protein 2; RhoGEF and pleckstrin domain-containing protein 2
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