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The antibody against FASTKD2 was raised in rabbit using the Fusion protein of Human FASTKD2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against FASTKD2 was raised in rabbit using the Fusion protein of Human FASTKD2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-30054A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FASTKD2 |
| Target Synonyms | FAKD2_HUMAN antibody; FAST kinase domain containing protein 2 antibody; FAST kinase domain-containing protein 2 antibody; FAST kinase domains 2 antibody; Fastkd2 antibody; KIAA0971 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human FASTKD2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NYY8 |
Uniprot Id
Q9NYY8
Target Species
Human
Target Name
FASTKD2
Target Full Name
FAST kinase domain-containing protein 2, mitochondrial
Target Function
Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. May play a role in mitochondrial apoptosis.
Target Subcellular Location
Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion matrix.
Target Protein Families
FAST kinase family
Target Tissue Specificity
Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle and thyroid.
Target Synonyms
FAKD2_HUMAN; FAST kinase domain containing protein 2; FAST kinase domain-containing protein 2; FAST kinase domains 2; Fastkd2; KIAA0971
Target Background
This gene encodes a protein that is localized in the mitochondrial inner compartment and that may play a role in mitochondrial apoptosis. Nonsense mutations have been reported to result in cytochrome c oxidase deficiency.
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