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The antibody against FBXL3 was raised in rabbit using the Peptide sequence around phosphorylation site of serine 320 (S-V-S(p)-K-D) derived from Human FBXL3. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi This antibody has been validated on ELISA, WB.
The antibody against FBXL3 was raised in rabbit using the Peptide sequence around phosphorylation site of serine 320 (S-V-S(p)-K-D) derived from Human FBXL3. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi This antibody has been validated on ELISA, WB.
$360.00
| Cat.No | ADC-40556A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FBXL3 |
| Form | Liquid | Species Reactivity | Mouse, Rat, Humann |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+) | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Peptide sequence around phosphorylation site of serine 320 (S-V-S(p)-K-D) derived from Human FBXL3. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UKT7 |
Uniprot Id
Q9UKT7
Target Species
Human
Target Name
FBXL3
Target Full Name
F-box/LRR-repeat protein 3
Target Function
Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF(FBXL3) complex is counteracted by the SCF(FBXL21) complex.
Target Subcellular Location
Nucleus. Cytoplasm. Note=Predominantly nuclear.
Target Tissue Specificity
Widely expressed.
Target Synonyms
F box and leucine rich repeat protein 3; F box and leucine rich repeat protein 3A; F box protein Fbl3a; F-box and leucine-rich repeat protein 3A; F-box/LRR-repeat protein 3; F-box/LRR-repeat protein 3A; FBL3; FBL3A; Fbxl3; FBXL3_HUMAN; FBXL3A
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