Rabbit anti-Human FCGR3B Polyclonal Antibody

The antibody against FCGR3B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FCGR3B (NP_000561.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11740A

Number

Cat.No	ADA-11740A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	FCGR3B
Target Synonyms	CD16; FCG3; CD16A; CD16b; FCGR3; CD16-I; FCGR3A; FCR-10; FCRIII; FCRIIIb; FCGR3B	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Jurkat, Mouse liver, Mouse spleen, Mouse thymus, Raji, Rat spleen, THP-1, U-937	Application	ELISA, WB

Cat.No

ADA-11740A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

FCGR3B

Target Synonyms

CD16; FCG3; CD16A; CD16b; FCGR3; CD16-I; FCGR3A; FCR-10; FCRIII; FCRIIIb; FCGR3B

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Jurkat, Mouse liver, Mouse spleen, Mouse thymus, Raji, Rat spleen, THP-1, U-937

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FCGR3B (NP_000561.3).	Target Species	Human
Uniprot ID	O75015	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FCGR3B (NP_000561.3).

Target Species

Human

Uniprot ID

O75015

Immunogen Sequence

Background Information

Uniprot Id

O75015
Target Species

Human
Target Name

FCGR3B
Target Full Name

Low affinity immunoglobulin gamma Fc region receptor III-B
Target Function

Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Target Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Secreted after cleavage.
Target Tissue Specificity

Expressed specifically by polymorphonuclear leukocytes (neutrophils). Also expressed by stimulated eosinophils.
Target Research Area

Immunology
Target Synonyms

CD16; CD16b; CD16b antigen ; Fc fragment of IgG low affinity IIIb receptor; Fc gamma receptor IIIb; Fc gamma RIII; Fc gamma RIII beta; Fc gamma RIIIb; Fc-gamma RIII; Fc-gamma RIII-beta; Fc-gamma RIIIb; FCG3; FCG3B_HUMAN; FCGR3; FCGR3B; FcR 10; FcR-10; FcR10; FcRIII; FcRIIIb; IGFR3; IgG Fc receptor III 1; IgG Fc receptor III-1; Low affinity immunoglobulin gamma Fc region receptor III B; Low affinity immunoglobulin gamma Fc region receptor III-B
Target Background

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.

Rabbit anti-Human FCGR3B Polyclonal Antibody

Specifications

Immunogen Information

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