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The antibody against FCHO1 was raised in rabbit using the Recombinant Human F-BAR domain only protein 1 protein (45-180AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against FCHO1 was raised in rabbit using the Recombinant Human F-BAR domain only protein 1 protein (45-180AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-06069A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FCHO1 |
| Target Synonyms | FCHO1 antibody; KIAA0290F-BAR domain only protein 1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human F-BAR domain only protein 1 protein (45-180AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14526 |
Uniprot Id
O14526
Target Species
Human
Target Name
FCHO1
Target Full Name
F-BAR domain only protein 1
Target Function
Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. May regulate Bmp signaling by regulating clathrin-mediated endocytosis of Bmp receptors.
Target Subcellular Location
Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Associated with forming but not mature clathrin-coated vesicles. The recruitment to coated-pits precede the one of clathrin and the adaptor protein complex AP-2. According to PubMed:17617719 it may also dynamically associate with Golgi/TGN membranes.
Target Protein Families
FCHO family
Target Synonyms
FCHO1; KIAA0290F-BAR domain only protein 1
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