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The antibody against FCRL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-100 of human FCRL2 (Q96LA5) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against FCRL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-100 of human FCRL2 (Q96LA5) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01423A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FCRL2 |
| Target Synonyms | FCRH2; IFGP4; IRTA4; SPAP1; CD307b; SPAP1A; SPAP1B; SPAP1C; FCRL2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Raji | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 20-100 of human FCRL2 (Q96LA5). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | LTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKI | Uniprot ID | Q96LA5 |
Uniprot Id
Q96LA5
Target Species
Human
Target Name
FCRL2
Target Full Name
Fc receptor-like protein 2
Target Function
May have an regulatory role in normal and neoplastic B cell development.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone
Target Synonyms
CD307b; Fc receptor homolog 2; Fc receptor like protein 2; Fc receptor-like protein 2; FcR-like protein 2; FcRH2; FCRL 2; FcRL2; FCRL2_HUMAN; IFGP family protein 4; IFGP4; Immunoglobulin receptor translocation associated 4 protein ; Immunoglobulin receptor translocation-associated protein 4; IRTA4; SH2 domain containing phosphatase anchor protein 1; SH2 domain-containing phosphatase anchor protein 1; SPAP1
Target Background
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
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