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The antibody against FCRL4 was raised in rabbit using the Recombinant Human Fc receptor-like protein 4 protein (20-387AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against FCRL4 was raised in rabbit using the Recombinant Human Fc receptor-like protein 4 protein (20-387AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-22702A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FCRL4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Fc receptor-like protein 4 protein (20-387AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96PJ5 |
Uniprot Id
Q96PJ5
Target Species
Human
Target Name
FCRL4
Target Full Name
Fc receptor-like protein 4
Target Function
May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response.
Target Involvement
A chromosomal aberration involving FCRL4 is found in non-Hodgkin lymphoma (NHG). Translocation t(1;1)(p36.3; q21.1-2).
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Specifically expressed by memory and monocytoid B-cells which populate spleen and lymph nodes. Preferentially expressed in memory B-cells associated with mucosal tissue (at protein level).
Target Research Area
Immunology
Target Synonyms
CD307d; Fc receptor homolog 4; Fc receptor like 4; Fc receptor like protein 4; Fc receptor-like protein 4; FcR like protein 4; FcR-like protein 4; FcRH4; FcRL4; FCRL4_HUMAN; hIFGP2; IFGP family protein 2; IGFP2; Immune receptor translocation associated protein 1; Immune receptor translocation-associated protein 1; Immunoglobulin superfamily receptor translocation associated 1; Immunoglobulin superfamily receptor translocation associated gene 1; IRTA1
Target Background
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.
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