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The antibody against FECH was raised in rabbit using the Human FECH as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against FECH was raised in rabbit using the Human FECH as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-53358A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FECH |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human FECH | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P22830 |
Uniprot Id
P22830
Target Species
Human
Target Name
FECH
Target Full Name
Ferrochelatase, mitochondrial
Target Function
Catalyzes the ferrous insertion into protoporphyrin IX.
Target Involvement
Erythropoietic protoporphyria (EPP)
Target Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Target Protein Families
Ferrochelatase family
Target Research Area
Cardiovascular
Target Synonyms
EPP; FCE; Fch; Fcl; fech; Ferrochelatase (protoporphyria); Ferrochelatase; Ferrochelatase mitochondrial; Heme synthase; Heme synthetase; HEMH_HUMAN; mitochondrial; Protoheme ferro lyase; Protoheme ferro-lyase; Protoporphyria
Target Background
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.
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