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Rabbit anti-Human Ferredoxin Reductase Polyclonal Antibody

The antibody against Ferredoxin Reductase was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 142-491 of human Ferredoxin Reductase(NP_077728.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-08497A

The antibody against Ferredoxin Reductase was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 142-491 of human Ferredoxin Reductase(NP_077728.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-08497A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFerredoxin Reductase
Target SynonymsADR; ADXR; ANOA; FDXRFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesHep G2, Mouse testis, Rat testisApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 142-491 of human Ferredoxin Reductase(NP_077728.3).Target SpeciesHuman
Uniprot IDP22570Immunogen Sequence
Background Information
  • Uniprot Id

    P22570

  • Target Species

    Human

  • Target Name

    FDXR

  • Target Full Name

    NADPH:adrenodoxin oxidoreductase, mitochondrial

  • Target Function

    Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

  • Target Subcellular Location

    Mitochondrion inner membrane; Peripheral membrane protein.

  • Target Protein Families

    Ferredoxin--NADP reductase type 1 family

  • Target Research Area

    Cell Biology

  • Target Synonyms

    Adrenodoxin reductase; ADRO_HUMAN; ADXR; AR; FDXR; Ferredoxin NADP(+) reductase; Ferredoxin reductase; Ferredoxin--NADP(+) reductase; mitochondrial; NADPH adrenodoxin oxidoreductase mitochondrial; NADPH:adrenodoxin oxidoreductase

  • Target Background

    This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants have been found for this gene.

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