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Rabbit anti-Human FEZF1 Polyclonal Antibody

The antibody against FEZF1 was raised in rabbit using the Recombinant Human Fez family zinc finger protein 1 protein (1-115AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

ADC-03537A

The antibody against FEZF1 was raised in rabbit using the Recombinant Human Fez family zinc finger protein 1 protein (1-115AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-03537A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFEZF1
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Fez family zinc finger protein 1 protein (1-115AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDA0PJY2
Background Information
  • Uniprot Id

    A0PJY2

  • Target Species

    Human

  • Target Name

    FEZF1

  • Target Full Name

    Fez family zinc finger protein 1

  • Target Function

    Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors.

  • Target Involvement

    Hypogonadotropic hypogonadism 22 with or without anosmia (HH22)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Krueppel C2H2-type zinc-finger protein family

  • Target Tissue Specificity

    Expressed in brain. Little or no expression in other tissues. Overexpressed specifically in gastric cancers. A 2- to 20-fold increase is found in over 50% of gastric cancer tissues.

  • Target Synonyms

    FEZ; FEZ family zinc finger 1; Fez family zinc finger protein 1; fez like; fezf1; FEZF1_HUMAN; Zinc finger protein 312 like; Zinc finger protein 312B

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