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Rabbit anti-Human FGF7 Polyclonal Antibody

The antibody against FGF7 was raised in rabbit using the Recombinant Human Fibroblast growth factor 7 protein (34-189AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-45504A

The antibody against FGF7 was raised in rabbit using the Recombinant Human Fibroblast growth factor 7 protein (34-189AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-45504A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFGF7
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Fibroblast growth factor 7 protein (34-189AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP21781
Background Information
  • Uniprot Id

    P21781

  • Target Species

    Human

  • Target Name

    FGF7

  • Target Full Name

    Fibroblast growth factor 7

  • Target Function

    Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Heparin-binding growth factors family

  • Target Tissue Specificity

    Epithelial cell.

  • Target Synonyms

    FGF 7; FGF-7; Fgf7; FGF7_HUMAN; Fibroblast growth factor 7; HBGF 7; HBGF-7; HBGF7; Heparin binding growth factor 7; Heparin-binding growth factor 7; Keratinocyte growth factor; KGF

  • Target Background

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

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