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The antibody against FGGY was raised in rabbit using the Recombinant Human FGGY carbohydrate kinase domain-containing protein (1-244AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, antigen affinity purified & affinity purified with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against FGGY was raised in rabbit using the Recombinant Human FGGY carbohydrate kinase domain-containing protein (1-244AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, antigen affinity purified & affinity purified with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-00566A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FGGY |
| Target Synonyms | FGGYFGGY carbohydrate kinase domain-containing protein antibody; EC 2.7.1.- antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Antigen Affinity purified & Affinity purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human FGGY carbohydrate kinase domain-containing protein (1-244AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96C11 |
Uniprot Id
Q96C11
Target Species
Human
Target Name
FGGY
Target Full Name
FGGY carbohydrate kinase domain-containing protein
Target Function
Catalyzes ATP-dependent phosphorylation of D-ribulose at C-5 to form D-ribulose 5-phosphate. Postulated to function in a metabolite repair mechanism by preventing toxic accumulation of free D-ribulose formed by non-specific phosphatase activities. Alternatively, may play a role in regulating D-ribulose 5-phosphate recycling in the pentose phosphate pathway. Can phosphorylate ribitol with low efficiency.
Target Involvement
Amyotrophic lateral sclerosis (ALS)
Target Protein Families
FGGY kinase family
Target Tissue Specificity
Expressed in kidney, lung and small intestine and to a lower extent in liver and detected in cerebrospinal fluid (at protein level).
Target Synonyms
FGGYFGGY carbohydrate kinase domain-containing protein; EC 2.7.1.-
Target Background
This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this association. Alternative splicing results in multiple transcript variants.
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