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The antibody against FHL5 was raised in rabbit using the Fusion protein of Human FHL5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against FHL5 was raised in rabbit using the Fusion protein of Human FHL5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-31101A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FHL5 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human FHL5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5TD97 |
Uniprot Id
Q5TD97
Target Species
Human
Target Name
FHL5
Target Full Name
Four and a half LIM domains protein 5
Target Function
May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
Target Subcellular Location
Nucleus. Note=Nuclei of round and elongated spermatids.
Target Tissue Specificity
Testis-specific (at protein level).
Target Synonyms
Activator of cAMP responsive element modulator (CREM) in testis; Activator of cAMP-responsive element modulator in testis; Activator of CREM in testis; FHL-5; Fhl5; FHL5 protein; FHL5_HUMAN; Four and a half LIM domains protein 5
Target Background
The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene. Polymorphisms in this gene may be associated with susceptibility for migraine headaches. Alternative splicing results in multiple transcript variants encoding the same protein.
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