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Rabbit anti-Human FIGNL1 Polyclonal Antibody

The antibody against FIGNL1 was raised in rabbit using the Human FIGNL1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-53344A

The antibody against FIGNL1 was raised in rabbit using the Human FIGNL1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-53344A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFIGNL1
Target SynonymsFIGNL1Fidgetin-like protein 1 antibody; EC 3.6.4.- antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman FIGNL1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ6PIW4
Background Information
  • Uniprot Id

    Q6PIW4

  • Target Species

    Human

  • Target Name

    FIGNL1

  • Target Full Name

    Fidgetin-like protein 1

  • Target Function

    Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner. May regulate osteoblast proliferation and differentiation. May play a role in the control of male meiosis dynamic.

  • Target Subcellular Location

    Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Together with RAD51 and a subset of H2A histone proteins, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) treatment (PubMed:23754376).

  • Target Protein Families

    AAA ATPase family

  • Target Research Area

    Cell Biology

  • Target Synonyms

    FIGNL1Fidgetin-like protein 1; EC 3.6.4.-

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