Rabbit anti-Human FILIP1L Polyclonal Antibody

The antibody against FILIP1L was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FILIP1L (NP_878913.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06799A

Number

Cat.No	ADA-06799A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	FILIP1L
Target Synonyms	DOC1; DOC-1; GIP90; GIP130; FILIP1L	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	A375, HT-29, Mouse ovary	Application	ELISA, WB

Cat.No

ADA-06799A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

FILIP1L

Target Synonyms

DOC1; DOC-1; GIP90; GIP130; FILIP1L

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

A375, HT-29, Mouse ovary

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FILIP1L (NP_878913.2).	Target Species	Human
Immunogen Sequence	MRSRGSDTEGSAQKKFPRHTKGHSFQGPKNMKHRQQDKDSPSESDVILPCPKAEKPHSGNGHQAEDLSRDDLLFLLSILEGELQARDEVIGILKAEKMDLALLEAQYGFVTPKKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLLEQEC	Uniprot ID	Q4L180

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FILIP1L (NP_878913.2).

Target Species

Human

Immunogen Sequence

MRSRGSDTEGSAQKKFPRHTKGHSFQGPKNMKHRQQDKDSPSESDVILPCPKAEKPHSGNGHQAEDLSRDDLLFLLSILEGELQARDEVIGILKAEKMDLALLEAQYGFVTPKKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLLEQEC

Uniprot ID

Q4L180

Background Information

Uniprot Id

Q4L180
Target Species

Human
Target Name

FILIP1L
Target Full Name

Filamin A-interacting protein 1-like
Target Function

Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.
Target Subcellular Location

Cytoplasm. Membrane. Nucleus.
Target Protein Families

FILIP1 family
Target Tissue Specificity

Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. D
Target Research Area

Cancer
Target Synonyms

130 kDa GPBP-interacting protein; 90 kDa GPBP-interacting protein; COL4A3BPIP; DOC-1; DOC1; Downregulated in ovarian cancer 1 81 kDa isoform; FIL1L_HUMAN; Filamin A-interacting protein 1-like; FILIP1L; GIP130; GIP130a; GIP130b; GIP130c; GIP90; GPBP interacting protein 90; Protein down-regulated in ovarian cancer 1
Target Background

Predicted to be located in cytoplasm; membrane; and nucleus.

Rabbit anti-Human FILIP1L Polyclonal Antibody

Specifications

Immunogen Information

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