Rabbit anti-Human FKBP14 Polyclonal Antibody

The antibody against FKBP14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-211 of human FKBP14 (NP_060416.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03528A

Number

Cat.No	ADA-03528A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	FKBP14
Target Synonyms	EDSKMH; FKBP22; IPBP12; EDSKSCL2; FKBP14	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, MCF7, Mouse testis, NCI-H460, Rat testis, U-87MG	Application	ELISA, WB

Cat.No

ADA-03528A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

FKBP14

Target Synonyms

EDSKMH; FKBP22; IPBP12; EDSKSCL2; FKBP14

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, MCF7, Mouse testis, NCI-H460, Rat testis, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 20-211 of human FKBP14 (NP_060416.1).	Target Species	Human
Immunogen Sequence	ALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFISAREFTYKHDEL	Uniprot ID	Q9NWM8

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 20-211 of human FKBP14 (NP_060416.1).

Target Species

Human

Immunogen Sequence

ALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFISAREFTYKHDEL

Uniprot ID

Q9NWM8

Background Information

Uniprot Id

Q9NWM8
Target Species

Human
Target Name

FKBP14
Target Full Name

Peptidyl-prolyl cis-trans isomerase FKBP14
Target Function

PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4-hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens.
Target Involvement

Ehlers-Danlos syndrome, with progressive kyphoscoliosis, myopathy, and hearing loss (EDSKMH)
Target Subcellular Location

Endoplasmic reticulum lumen.
Target Research Area

Others
Target Synonyms

22 kDa FK506 binding protein; 22 kDa FK506-binding protein; 22 kDa FKBP; FK506 binding protein 14 (22 kDa); FK506 binding protein 14; FK506-binding protein 14; FKB14_HUMAN; FKBP 22; FKBP-14; FKBP-22; FKBP14; FKBP22; FLJ20731; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP14; PPIase; PPIase FKBP14; Rotamase
Target Background

The protein encoded by this gene is a member of the FK506-binding protein family of peptidyl-prolyl cis-trans isomerases. The encoded protein is found in the lumen of the endoplasmic reticulum, where it is thought to accelerate protein folding. Defects in this gene are a cause of a type of Ehlers-Danlos syndrome (EDS). Both a protein-coding variant and noncoding variants are transcribed from this gene.

Rabbit anti-Human FKBP14 Polyclonal Antibody

Specifications

Immunogen Information

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