Rabbit anti-Human FLOT2 Polyclonal Antibody

Uniprot Id

Q14254

Target Species

Human

Target Name

FLOT2

Target Full Name

Flotillin-2

Target Function

May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.

Target Subcellular Location

Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Endosome. Membrane; Lipid-anchor. Note=Membrane-associated protein of caveolae.

Target Protein Families

Band 7/mec-2 family, Flotillin subfamily

Target Tissue Specificity

In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carci

Target Research Area

Neuroscience

Target Synonyms

ECS-1; ECS1; Epidermal surface antigen 1; Epidermal surface antigen; ESA; ESA1; Flot2; FLOT2_HUMAN; Flotillin 2 (epidermal surface antigen 1); Flotillin-2; M17S1; Membrane component chromosome 17 surface marker 1; Membrane component chromosome 17 surface marker 1 homolog; membrane component; chromosome 17; surface marker 1 (35kD protein identified by monoclonal ECS-1); Membrane component; chromosome 17; surface marker 1; REG-1; Reggie-1; Reggie-2

Target Background

Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling.