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Rabbit anti-Human FNBP1L Polyclonal Antibody

The antibody against FNBP1L was raised in rabbit using the Human FNBP1L as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-53327A

The antibody against FNBP1L was raised in rabbit using the Human FNBP1L as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-53327A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFNBP1L
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., 0.02% Sodium Azide, 0.1M Glycine, 0.1M NaHCO3
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman FNBP1LTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ5T0N5
Background Information
  • Uniprot Id

    Q5T0N5

  • Target Species

    Human

  • Target Name

    FNBP1L

  • Target Full Name

    Formin-binding protein 1-like

  • Target Function

    Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens.

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cytoplasmic vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side.

  • Target Protein Families

    FNBP1 family

  • Target Synonyms

    C1orf39; FBP1L_HUMAN; FNBP 1L; fnbp1l; Formin binding protein 1 like; Formin-binding protein 1-like; TOCA 1; Toca-1; TOCA1; Transducer of Cdc42 dependent actin assembly 1; Transducer of Cdc42 dependent actin assembly protein 1; Transducer of Cdc42-dependent actin assembly protein 1

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