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Rabbit anti-Human FOSB Polyclonal Antibody

The antibody against FOSB was raised in rabbit using the Synthetic peptide of Human FOSB as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-28511A

The antibody against FOSB was raised in rabbit using the Synthetic peptide of Human FOSB as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-28511A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFOSB
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human FOSBTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP53539
Background Information
  • Uniprot Id

    P53539

  • Target Species

    Human

  • Target Name

    FOSB

  • Target Full Name

    Protein FosB

  • Target Function

    FosB interacts with Jun proteins enhancing their DNA binding activity.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    BZIP family, Fos subfamily

  • Target Research Area

    Cancer

  • Target Synonyms

    Activator protein 1; AP 1; DKFZp686C0818; FBJ murine osteosarcoma viral oncogene homolog B; fosB; FOSB_HUMAN; G0/G1 switch regulatory protein 3; G0S3; GOS 3; GOS B; GOS3; GOSB; MGC42291; Oncogene FOS B; Oncogene FOSB; Protein fos B; Protein fosB

  • Target Background

    The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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