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Rabbit anti-Human FOSB Polyclonal Antibody

The antibody against FOSB was raised in rabbit using the Synthetic peptide of Human FOSB as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-28512A

The antibody against FOSB was raised in rabbit using the Synthetic peptide of Human FOSB as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-28512A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFOSB
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human FOSBTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP53539
Background Information
  • Uniprot Id

    P53539

  • Target Species

    Human

  • Target Name

    FOSB

  • Target Full Name

    Protein FosB

  • Target Function

    FosB interacts with Jun proteins enhancing their DNA binding activity.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    BZIP family, Fos subfamily

  • Target Research Area

    Cancer

  • Target Synonyms

    Activator protein 1; AP 1; DKFZp686C0818; FBJ murine osteosarcoma viral oncogene homolog B; fosB; FOSB_HUMAN; G0/G1 switch regulatory protein 3; G0S3; GOS 3; GOS B; GOS3; GOSB; MGC42291; Oncogene FOS B; Oncogene FOSB; Protein fos B; Protein fosB

  • Target Background

    The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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