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The antibody against FOXA3 was raised in rabbit using the Recombinant Human Hepatocyte nuclear factor 3-gamma protein (220-336AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against FOXA3 was raised in rabbit using the Recombinant Human Hepatocyte nuclear factor 3-gamma protein (220-336AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-04363A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FOXA3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Biotin conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Hepatocyte nuclear factor 3-gamma protein (220-336AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P55318 |
Uniprot Id
P55318
Target Species
Human
Target Name
FOXA3
Target Full Name
Hepatocyte nuclear factor 3-gamma
Target Function
Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; binds to and activates transcription from the G6PC1 promoter. Binds to the CYP3A4 promoter and activates its transcription in cooperation with CEBPA. Binds to the CYP3A7 promoter together with members of the CTF/NF-I family. Involved in regulation of neuronal-specific transcription. May be involved in regulation of spermatogenesis.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expressed in erythroleukemia and hepatoma cell lines and in liver and pancreas. Not expressed in any other cell lines or tissues examined.
Target Synonyms
FKHH3; Fork head-related protein FKH H3; forkhead box A3; Forkhead box protein A3; Foxa3; FOXA3_HUMAN; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3; hepatocyte nuclear factor 3 gamma; Hepatocyte nuclear factor 3-gamma; HNF-3-gamma; HNF-3G; HNF3B; HNF3G; TCF-3G; TCF3G; Transcription factor 3G
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