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The antibody against FOXE1 was raised in rabbit using the Synthesized peptide derived from internal of Human TTF2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IF.
The antibody against FOXE1 was raised in rabbit using the Synthesized peptide derived from internal of Human TTF2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IF.
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Immunofluorescence analysis of A549 cells, using TTF2 antibody.
| Cat.No | ADC-40796A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FOXE1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IF | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human TTF2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O00358 |
Uniprot Id
O00358
Target Species
Human
Target Name
FOXE1
Target Full Name
Forkhead box protein E1
Target Function
Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression.
Target Involvement
Bamforth-Lazarus syndrome (BLS); Thyroid cancer, non-medullary, 4 (NMTC4)
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas.
Target Synonyms
FKH L15; FKHL 15; FKHL15; Forkhead (Drosophila) like 15; Forkhead box E1; Forkhead box E2; Forkhead box protein E1; Forkhead box protein E2; Forkhead drosophila homolog like 15; Forkhead like 15; Forkhead related protein FKHL 15; Forkhead related protein FKHL15; Forkhead-related protein FKHL15; FOX E1; FOX E2; FOXE 1; FOXE 2; FOXE1; FOXE1_HUMAN; FOXE2; HFKH 4; HFKH4; HFKL 5; HFKL5; HNF-3/fork head-like protein 5; Thyroid transcription factor 2; TITF 2; TITF2; TTF 2; TTF-2; TTF2
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