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The antibody against FOXG1 was raised in rabbit using the Recombinant Human Forkhead box protein G1 protein (183-292AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against FOXG1 was raised in rabbit using the Recombinant Human Forkhead box protein G1 protein (183-292AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human heart tissue using FOXG1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using FOXG1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-16026A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FOXG1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Forkhead box protein G1 protein (183-292AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P55316 |
Uniprot Id
P55316
Target Species
Human
Target Name
FOXG1
Target Full Name
Forkhead box protein G1
Target Function
Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
Target Involvement
Rett syndrome congenital variant (RTTCV)
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expression is restricted to the neurons of the developing telencephalon.
Target Research Area
Others
Target Synonyms
BF-1; BF-2; BF1; BF2; Brain factor 1; Brain factor 2; FHKL; FKH2; FKHL1; FKHL2; FKHL3; FKHL4; Forkhead box protein G1; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; Forkhead like 1; Forkhead like 2; Forkhead like 3; Forkhead like 4; Forkhead-related protein FKHL1; Forkhead-related protein FKHL2; Forkhead-related protein FKHL3; FOXG1; FOXG1_HUMAN; FOXG1A; FOXG1B; FOXG1C; HBF 1; HBF G2; hBF-2; HBF2; HFK1; HFK2; HFK3; KHL2; Oncogene QIN; QIN
Target Background
This locus encodes a member of the fork-head transcription factor family. The encoded protein, which functions as a transcriptional repressor, is highly expressed in neural tissues during brain development. Mutations at this locus have been associated with Rett syndrome and a diverse spectrum of neurodevelopmental disorders defined as part of the FOXG1 syndrome. This gene is disregulated in many types of cancer and is the target of multiple microRNAs that regulate the proliferation of tumor cells.
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