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The antibody against FRS3 was raised in rabbit using the Recombinant Human Fibroblast growth factor receptor substrate 3 protein (101-400AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against FRS3 was raised in rabbit using the Recombinant Human Fibroblast growth factor receptor substrate 3 protein (101-400AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human cervical cancer using FRS3 Antibody at dilution of 1:1002
| Cat.No | ADC-22043A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FRS3 |
| Target Synonyms | FRS3Fibroblast growth factor receptor substrate 3 antibody; FGFR substrate 3 antibody; FGFR-signaling adaptor SNT2 antibody; Suc1-associated neurotrophic factor target 2 antibody; SNT-2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Fibroblast growth factor receptor substrate 3 protein (101-400AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43559 |
Uniprot Id
O43559
Target Species
Human
Target Name
FRS3
Target Full Name
Fibroblast growth factor receptor substrate 3
Target Function
Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
Target Subcellular Location
Membrane; Lipid-anchor.
Target Synonyms
FRS3Fibroblast growth factor receptor substrate 3; FGFR substrate 3; FGFR-signaling adaptor SNT2; Suc1-associated neurotrophic factor target 2; SNT-2
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