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The antibody against FSCN2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human FSCN2 (NP_036550.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against FSCN2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human FSCN2 (NP_036550.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00247A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FSCN2 |
| Target Synonyms | RFSN; RP30; FSCN2 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human FSCN2 (NP_036550.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O14926 | Immunogen Sequence |
Uniprot Id
O14926
Target Species
Human
Target Name
FSCN2
Target Full Name
Fascin-2
Target Function
Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.
Target Involvement
Retinitis pigmentosa 30 (RP30)
Target Subcellular Location
Cytoplasm, cytoskeleton. Cell projection, stereocilium.
Target Protein Families
Fascin family
Target Tissue Specificity
Localized specifically in the outer and inner segments of the photoreceptor cells in the retina.
Target Synonyms
Fascin homolog 2; actin bundling protein; retinal Strongylocentrotus purpuratus; Fascin Strongylocentrotus purpuratus homolog 2 actin bundling protein; retinal; Fascin-2; FSCN2; FSCN2_HUMAN; Retinal fascin; RFSN; RP30
Target Background
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.
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