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The antibody against FSCN2 was raised in rabbit using the Recombinant Human Fascin-2 protein (1-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against FSCN2 was raised in rabbit using the Recombinant Human Fascin-2 protein (1-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-22042A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FSCN2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Fascin-2 protein (1-300AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14926 |
Uniprot Id
O14926
Target Species
Human
Target Name
FSCN2
Target Full Name
Fascin-2
Target Function
Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.
Target Involvement
Retinitis pigmentosa 30 (RP30)
Target Subcellular Location
Cytoplasm, cytoskeleton. Cell projection, stereocilium.
Target Protein Families
Fascin family
Target Tissue Specificity
Localized specifically in the outer and inner segments of the photoreceptor cells in the retina.
Target Synonyms
Fascin homolog 2; actin bundling protein; retinal Strongylocentrotus purpuratus; Fascin Strongylocentrotus purpuratus homolog 2 actin bundling protein; retinal; Fascin-2; FSCN2; FSCN2_HUMAN; Retinal fascin; RFSN; RP30
Target Background
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.
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