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The antibody against FSHB was raised in rabbit using the Recombinant Human Follitropin subunit beta protein (19-129AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against FSHB was raised in rabbit using the Recombinant Human Follitropin subunit beta protein (19-129AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-50096A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FSHB |
| Target Synonyms | FSHBFollitropin subunit beta antibody; Follicle-stimulating hormone beta subunit antibody; FSH-B antibody; FSH-beta antibody; Follitropin beta chain antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Follitropin subunit beta protein (19-129AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P01225 |
Uniprot Id
P01225
Target Species
Human
Target Name
FSHB
Target Full Name
Follitropin subunit beta
Target Function
Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
Target Involvement
Hypogonadotropic hypogonadism 24 without anosmia (HH24)
Target Subcellular Location
Secreted.
Target Protein Families
Glycoprotein hormones subunit beta family
Target Synonyms
HH24; FSHB
Target Background
The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein.
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