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The antibody against FSHR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 631-695 of human FSHR (NP_000136.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against FSHR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 631-695 of human FSHR (NP_000136.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-12764A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FSHR |
| Target Synonyms | LGR1; ODG1; FSHR1; FSHRO; FSHR | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 631-695 of human FSHR (NP_000136.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | KNFRRDFFILLSKCGCYEMQAQIYRTETSSTVHNTHPRNGHCSSAPRVTSGSTYILVPLSHLAQN | Uniprot ID | P23945 |
Uniprot Id
P23945
Target Species
Human
Target Name
FSHR
Target Full Name
Follicle-stimulating hormone receptor
Target Function
G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
Target Involvement
Ovarian dysgenesis 1 (ODG1); Ovarian hyperstimulation syndrome (OHSS)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family, FSH/LSH/TSH subfamily
Target Tissue Specificity
Sertoli cells and ovarian granulosa cells.
Target Research Area
G-protein coupled receptor, Neuroscience
Target Synonyms
Follicle stimulating hormone receptor; Follicle stimulating hormone receptor isoform 1; Follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; FSH-R; Fshr; FSHR_HUMAN; FSHRO; LGR1; MGC141667; MGC141668; ODG1; ovarian dysgenesis 1
Target Background
The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.
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