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The antibody against FUCA1 was raised in rabbit using the Recombinant Human Tissue alpha-L-fucosidase protein (32-158AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against FUCA1 was raised in rabbit using the Recombinant Human Tissue alpha-L-fucosidase protein (32-158AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human liver tissue using FUCA1 Antibody at dilution of 1:100
| Cat.No | ADC-11164A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Fuca1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tissue alpha-L-fucosidase protein (32-158AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P04066 |
Uniprot Id
P04066
Target Species
Human
Target Name
FUCA1
Target Full Name
Tissue alpha-L-fucosidase
Target Function
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
Target Involvement
Fucosidosis (FUCA1D)
Target Subcellular Location
Lysosome.
Target Protein Families
Glycosyl hydrolase 29 family
Target Synonyms
Alpha L fucosidase I; Alpha L fucoside fucohydrolase; Alpha-L-fucosidase 1; Alpha-L-fucosidase I; Alpha-L-fucoside fucohydrolase 1; FUCA; FUCA1; FUCO_HUMAN; fucosidase; alpha-L; tissue; fucosidase; alpha-L- 1; tissue; Tissue alpha L fucosidase; Tissue alpha-L-fucosidase
Target Background
The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.
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