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The antibody against FXR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 310-539 of human FXR1 (NP_001013456.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against FXR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 310-539 of human FXR1 (NP_001013456.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
Immunofluorescence analysis of HeLa cells using FXR1 Rabbit pAb at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
| Cat.No | ADA-00280A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FXR1 |
| Target Synonyms | FXR1P; CMYP9A; CMYP9B; MYOPMIL; MYORIBF; FXR1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 310-539 of human FXR1 (NP_001013456.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P51114 | Immunogen Sequence |
Uniprot Id
P51114
Target Species
Human
Target Name
FXR1
Target Full Name
RNA-binding protein FXR1
Target Function
RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs.
Target Subcellular Location
Cytoplasm, cytosol.
Target Protein Families
FMR1 family
Target Tissue Specificity
Expressed in all tissues examined including heart, brain, kidney and testis.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Fragile X mental retardation autosomal homolog 1; Fragile X mental retardation syndrome related protein 1; Fragile X mental retardation syndrome-related protein 1; FXR1; FXR1_HUMAN; FXR1P; hFXR1p
Target Background
The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.
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