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The antibody against GABRQ was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 350-600 of human GABRQ (NP_061028.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GABRQ was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 350-600 of human GABRQ (NP_061028.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03533A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GABRQ |
| Target Synonyms | THETA; GABRQ | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Jurkat | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 350-600 of human GABRQ (NP_061028.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UN88 | Immunogen Sequence |
Uniprot Id
Q9UN88
Target Species
Human
Target Name
GABRQ
Target Full Name
Gamma-aminobutyric acid receptor subunit theta
Target Function
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Target Subcellular Location
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Target Protein Families
Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRQ sub-subfamily
Target Synonyms
GABRQ; Gamma-aminobutyric acid receptor subunit theta; GABA(A) receptor subunit theta
Target Background
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes the theta subunit of the GABA A receptor. The gene is mapped to chromosome Xq28 in a cluster of genes including those that encode the alpha 3 and epsilon subunits of the GABA A receptor.
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