Rabbit anti-Human GABRR1 Polyclonal Antibody

The antibody against GABRR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human GABRR1 (NP_002033.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04234A

Number

Cat.No	ADA-04234A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	GABRR1
Target Synonyms	GABRR1	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, Mouse brain	Application	ELISA, WB

Cat.No

ADA-04234A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

GABRR1

Target Synonyms

GABRR1

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, Mouse brain

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human GABRR1 (NP_002033.2).	Target Species	Human
Immunogen Sequence	MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREVHEDAHKQVSPILRRSPDITKSPLTKSEQLLR	Uniprot ID	P24046

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human GABRR1 (NP_002033.2).

Target Species

Human

Immunogen Sequence

MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREVHEDAHKQVSPILRRSPDITKSPLTKSEQLLR

Uniprot ID

P24046

Background Information

Uniprot Id

P24046
Target Species

Human
Target Name

GABRR1
Target Full Name

Gamma-aminobutyric acid receptor subunit rho-1
Target Function

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.
Target Subcellular Location

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Target Protein Families

Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRR1 sub-subfamily
Target Tissue Specificity

Highly expressed in the retina and in a lesser extent in brain, lung and thymus.
Target Synonyms

bA135P14.1 (gamma-aminobutyric acid (GABA) receptor rho 1); GABA(A) receptor subunit rho-1; GABA(C) receptor; GABRR1; gamma aminobutyric acid receptor rho 1; gamma-aminobutyric acid (GABA) A receptor rho-1; gamma-aminobutyric acid (GABA) receptor rho 1; Gamma-aminobutyric acid receptor subunit rho-1; GBRR1_HUMAN; MGC163216
Target Background

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human GABRR1 Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human GABRR1 Polyclonal Antibody Now

Related Products