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Rabbit anti-Human GABRR1 Polyclonal Antibody

The antibody against GABRR1 was raised in rabbit using the Recombinant Human Gamma-aminobutyric acid receptor subunit rho-1 protein (365-465AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-17570A

The antibody against GABRR1 was raised in rabbit using the Recombinant Human Gamma-aminobutyric acid receptor subunit rho-1 protein (365-465AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-17570A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGABRR1
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Gamma-aminobutyric acid receptor subunit rho-1 protein (365-465AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP24046
Background Information
  • Uniprot Id

    P24046

  • Target Species

    Human

  • Target Name

    GABRR1

  • Target Full Name

    Gamma-aminobutyric acid receptor subunit rho-1

  • Target Function

    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.

  • Target Subcellular Location

    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRR1 sub-subfamily

  • Target Tissue Specificity

    Highly expressed in the retina and in a lesser extent in brain, lung and thymus.

  • Target Synonyms

    bA135P14.1 (gamma-aminobutyric acid (GABA) receptor rho 1); GABA(A) receptor subunit rho-1; GABA(C) receptor; GABRR1; gamma aminobutyric acid receptor rho 1; gamma-aminobutyric acid (GABA) A receptor rho-1; gamma-aminobutyric acid (GABA) receptor rho 1; Gamma-aminobutyric acid receptor subunit rho-1; GBRR1_HUMAN; MGC163216

  • Target Background

    GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene.

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