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The antibody against GADD45G was raised in rabbit using the Recombinant Human Growth arrest and DNA damage-inducible protein GADD45 gamma protein (1-159AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against GADD45G was raised in rabbit using the Recombinant Human Growth arrest and DNA damage-inducible protein GADD45 gamma protein (1-159AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human lung cancer using GADD45G Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue using GADD45G Antibody at dilution of 1:1002
| Cat.No | ADC-44820A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GADD45G |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Growth arrest and DNA damage-inducible protein GADD45 gamma protein (1-159AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O95257 |
Uniprot Id
O95257
Target Species
Human
Target Name
GADD45G
Target Full Name
Growth arrest and DNA damage-inducible protein GADD45 gamma
Target Function
Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
Target Protein Families
GADD45 family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
CR6; Cytokine responsive protein CR6; Cytokine-responsive protein CR6; DDIT-2; DDIT2; DNA damage-inducible transcript 2 protein; GA45G_HUMAN; Gadd45g; Growth arrest and DNA damage inducible gamma ; Growth arrest and DNA damage-inducible protein GADD45 gamma; GRP17
Target Background
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
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