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Rabbit anti-Human GAK Polyclonal Antibody

The antibody against GAK was raised in rabbit using the Human GAK as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-48497A

The antibody against GAK was raised in rabbit using the Human GAK as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-48497A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGAK
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman GAKTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO14976
Background Information
  • Uniprot Id

    O14976

  • Target Species

    Human

  • Target Name

    GAK

  • Target Full Name

    Cyclin-G-associated kinase

  • Target Function

    Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.

  • Target Subcellular Location

    Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network. Cell junction, focal adhesion. Note=Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focal adhesions.

  • Target Protein Families

    Protein kinase superfamily, Ser/Thr protein kinase family

  • Target Tissue Specificity

    Ubiquitous. Highest in testis.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    Auxilin 2; Cyclin G associated kinase; Cyclin-G-associated kinase; DNAJ26; DNAJC26; EC 2.7.11.1; FLJ16629; FLJ40395; GAK; GAK protein; GAK_HUMAN; MGC99654

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