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The antibody against Galactosidase alpha (GLA) was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-429 of human Galactosidase alpha (Galactosidase alpha (GLA)) (NP_000160.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against Galactosidase alpha (GLA) was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-429 of human Galactosidase alpha (Galactosidase alpha (GLA)) (NP_000160.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05899A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Galactosidase alpha (GLA) |
| Target Synonyms | GALA; Galactosidase alpha (GLA) | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 150-429 of human Galactosidase alpha (Galactosidase alpha (GLA)) (NP_000160.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P06280 | Immunogen Sequence |
Uniprot Id
P06280
Target Species
Human
Target Name
GLA
Target Full Name
Alpha-galactosidase A
Target Function
Catalyzes the hydrolysis of glycosphingolipids and participates in their degradation in the lysosome.
Target Involvement
Fabry disease (FD)
Target Subcellular Location
Lysosome.
Target Protein Families
Glycosyl hydrolase 27 family
Target Research Area
Cardiovascular
Target Synonyms
AGAL_HUMAN; Agalsidase alfa; Alpha D galactosidase A; Alpha D galactoside galactohydrolase 1; Alpha D galactoside galactohydrolase; Alpha gal A; Alpha galactosidase A; Alpha-D-galactosidase A; Alpha-D-galactoside galactohydrolase; Alpha-galactosidase A; GALA; Galactosidase; alpha; GLA; GLA protein; Melibiase
Target Background
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
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