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Rabbit anti-Human GALNT15 Polyclonal Antibody

The antibody against GALNT15 was raised in rabbit using the Human GALNTL2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-54619A

The antibody against GALNT15 was raised in rabbit using the Human GALNTL2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-54619A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGALNT15
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman GALNTL2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8N3T1
Background Information
  • Uniprot Id

    Q8N3T1

  • Target Species

    Human

  • Target Name

    GALNT15

  • Target Full Name

    Polypeptide N-acetylgalactosaminyltransferase 15

  • Target Function

    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate.

  • Target Subcellular Location

    Golgi apparatus membrane; Single-pass type II membrane protein.

  • Target Protein Families

    Glycosyltransferase 2 family, GalNAc-T subfamily

  • Target Tissue Specificity

    Widely expressed. Highly expressed in small intestine, placenta, spleen, cerebral cortex and ovary. Expressed at intermediate level in uterus, mammary gland, stomach, cerebellum and whole brain. Weakly expressed in fetal brain, bone marrow, thyroid gland,

  • Target Synonyms

    GALNT15; GALNTL2; UNQ770/PRO1564Polypeptide N-acetylgalactosaminyltransferase 15; EC 2.4.1.41; Polypeptide GalNAc transferase-like protein 2; GalNAc-T-like protein 2; pp-GaNTase-like protein 2; Polypeptide N-acetylgalactosaminyltransferase-like protein 2; Protein-UDP acetylgalactosaminyltransferase-like protein 2; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2

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