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The antibody against GALT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-379 of human GALT (NP_000146.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GALT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-379 of human GALT (NP_000146.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-13667A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GALT |
| Target Synonyms | GALT; LT | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-379 of human GALT (NP_000146.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P07902 | Immunogen Sequence |
Uniprot Id
P07902
Target Species
Human
Target Name
GALT
Target Full Name
Galactose-1-phosphate uridylyltransferase
Target Function
Plays an important role in galactose metabolism.
Target Involvement
Galactosemia (GALCT)
Target Protein Families
Galactose-1-phosphate uridylyltransferase type 1 family
Target Research Area
Metabolism
Target Synonyms
Gal 1 P uridylyltransferase; Gal-1-P uridylyltransferase; Galactose 1 phosphate uridyl transferase; Galactose 1 phosphate uridylyltransferase; Galactose-1-phosphate uridylyltransferase; GALT; GALT_HUMAN; UDP glucose hexose 1 phosphate uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase
Target Background
Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene.
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