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The antibody against GAN was raised in rabbit using the Recombinant Human Gigaxonin protein (1-240AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against GAN was raised in rabbit using the Recombinant Human Gigaxonin protein (1-240AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human breast cancer using GAN Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using GAN Antibody at dilution of 1:1002
| Cat.No | ADC-40470A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GAN |
| Target Synonyms | FLJ38059 antibody; GAN (gene name) antibody; GAN antibody; GAN_HUMAN antibody; GAN1 (gene name) antibody; Gigaxonin antibody; Kelch-like protein 16 antibody; KLHL16 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Gigaxonin protein (1-240AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H2C0 |
Uniprot Id
Q9H2C0
Target Species
Human
Target Name
GAN
Target Full Name
Gigaxonin
Target Function
Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.
Target Involvement
Giant axonal neuropathy 1, autosomal recessive (GAN1)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton.
Target Tissue Specificity
Expressed in brain, heart and muscle.
Target Synonyms
FLJ38059; GAN (gene name); GAN; GAN_HUMAN; GAN1 (gene name); Gigaxonin; Kelch-like protein 16; KLHL16
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