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The antibody against GANAB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GANAB (NP_001265123.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against GANAB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GANAB (NP_001265123.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-10266A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GANAB |
| Target Synonyms | G2AN; GIIA; PKD3; GLUII; GANAB | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Rat brain, HepG2, Mouse brain, Mouse liver, Raji, U-87MG | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GANAB (NP_001265123.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q14697 | Immunogen Sequence |
Uniprot Id
Q14697
Target Species
Human
Target Name
GANAB
Target Full Name
Neutral alpha-glucosidase AB
Target Function
Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia.
Target Involvement
Polycystic kidney disease 3 (PKD3)
Target Subcellular Location
Endoplasmic reticulum. Golgi apparatus. Melanosome.
Target Protein Families
Glycosyl hydrolase 31 family
Target Tissue Specificity
Detected in placenta. Isoform 1 and isoform 2 are expressed in the kidney and liver.
Target Synonyms
Alpha glucosidase II alpha subunit; Alpha-glucosidase 2; G2AN; GANAB; GANAB_HUMAN; Glu II; Glucosidase alpha neutral AB; Glucosidase II alpha; Glucosidase II subunit alpha; GluII; KIAA0088; Neutral alpha glucosidase AB; Neutral alpha glucosidase AB precursor ; Neutral alpha-glucosidase AB
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