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The antibody against GAS2 was raised in rabbit using the Fusion protein of Human GAS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against GAS2 was raised in rabbit using the Fusion protein of Human GAS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-31920A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GAS2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human GAS2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43903 |
Uniprot Id
O43903
Target Species
Human
Target Name
GAS2
Target Full Name
Growth arrest-specific protein 2
Target Function
May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process.
Target Subcellular Location
Cytoplasm, cytoskeleton, stress fiber. Membrane; Peripheral membrane protein.
Target Protein Families
GAS2 family
Target Tissue Specificity
Ubiquitously expressed with highest levels in liver, lung, and kidney. Not found in spleen.
Target Synonyms
GAS 2; GAS-2; Gas2; GAS2_HUMAN; Growth arrest specific 2; Growth arrest specific protein 2; Growth arrest-specific protein 2; MGC32610
Target Background
The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants.
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